Tag: University of Pennsylvania

CAR T cell stemness and metabolism are improved by FOXO1

Researchers from the University of Pennsylvania have isolated human CD4 and CD8 T cells from healthy donors and isolated human CD45+ cells from NSG mice. A total of 1.5 lakh CD5+ cells were slow-frozen in BamBanker medium. Ten thousand CAR T cells were washed in ice-cold PBS and then subjected to nuclei isolation with the following lysis buffer.

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For the first time, a Pig’sKidney was transplant into a person

A US hospital said that it transplanted a pig liver into a human using gene-edited pig. The organ circulated the person’s blood for three days. In January, a team at the University of Pennsylvania in Philadelphia connected a clinically dead person to a genetically modified pig’s liver located outside their body. The organ circulated the person’s blood for three days.

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