Tag: hypergeometric test
Large-scale comparisons of genes and diseases
To determine the colocalization of coronavirus variants, we identified a 95% credible set of variants likely to include the causal variant76. We identified primary associations through clumping 1 Mb around the significant variants using PLINK60. An enrichment analysis hypergeometric test was performed to estimate enrichment of the associated pQTL variants in specific consequence or regulatory genomic regions.
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