Tag: embryonic stem cell
Clinical classification of the BRCA2 variant is based on genome editing
A machine learning-based algorithm has been used to predict the risk of breast and ovarian cancer in women with BRCA2 variants, based on genome-wide transcriptome data. A computational model was used for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays. Genetic variants in BRCA2 are associated with breast cancer and ovarian cancer, respectively.
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