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This is the first time in history that Earth has broken the 1.5 C climate limit
An analysis of climate data from NASA’s Goddard Institute for Space Studies has revealed that temperatures in the world’s most extreme areas in the past two years are the warmest on record. The temperature extremes were recorded between July 1 and September 30 last year and between July 1 and September 30 2021 and July 1 to September 30 2018.
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The Hollywood Hills were affected by more fires in Southern California
US President Joe Biden on Wednesday said that “all federal assistance needs to be provided to California” to deal with the wildfires that have broken out in the state. “FEMA has approved a fire-management grant to help reimburse the State of California for immediate costs of fighting the fires,” he added. At least six people have died in the fires.
Read MoreMore fires are sparking in Southern California and spreading to the Hollywood Hills
The winds in US’ Los Angeles and Ventura counties, where multiple wildfires are burning, are expected to reach gusts of up to 100kmph. “The typical strengths of…winds are on…order of…30 to 60 mph when they occur a couple times a year,” National Weather Service (NWS) LA/Oxnard Chief Meteorologist Ariel Cohen said. Red flag warnings are in effect through Friday.
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Human genome editing needs to be discussed
Polygenic gene editing is a large concern among polygenic diseases advocates and also because no country currently allows genome editing in a human embryo. Individuals with edited genomes have a lower risk of disease. Although collectivist considerations should inform the values of governments and the goals they pursue, it is also important that HPE not be implemented in ways that decrease social cohesion.
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Clinical classification of the BRCA2 variant is based on genome editing
A machine learning-based algorithm has been used to predict the risk of breast and ovarian cancer in women with BRCA2 variants, based on genome-wide transcriptome data. A computational model was used for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays. Genetic variants in BRCA2 are associated with breast cancer and ovarian cancer, respectively.
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There is a foundation of transcription for human cell types
A model was used to learn regulatory grammar in the GET architecture using chromatin accessibility data from a variety of human cell types. The model was trained on the fetal accessibility and expression atlas and was able to complete in 8 h. It is possible to perform large-scale screening with the help of inference for genes in a single cell type.
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embryo editing against disease is unsafe and is not proven
Researchers from Australia, China and the US have examined the possibility of editing genomes of human embryos in the future. They found that in some cases, editing a single variant associated with a polygenic disease can have strong effects and that editing up to ten genes associated with a disease can reduce its lifetime prevalence by an order of magnitude.
Read MoreWinter illnesses return with a vengeance
Human metapneumovirus (hMPV) has a seasonal spike in the US after the first outbreak. While hMPV levels in the US are currently low, it accounts for less than 2% of weekly positive tests for respiratory viruses, based on CDC’s latest data. The country also experienced a sudden post-pandemic jump in hMPV infections during the winter of 2022-23.
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Las Vegas police released logs from the crime scene of the Cybertruck explosion
Matthew Livelsberger, an Army Green Beret with two deployments in Afghanistan, was investigating the New Year’s Eve explosion in front of the Trump Hotel in Las Vegas using generative AI technique, according to the police. Livelsberger had left a note that said the explosion was designed to be a “wake-up call” for the nation’s troubles. Livelsberger died in the explosion.
Read MoreIt has been a challenge trying to prevent vehicular attacks
A man who rammed into a crowd of people on New Year’s Day in New Orleans,Louisiana had used “smart glasses to record a video”, the FBI said on Sunday. The man was in the area before and used “smart glasses” to record video, it added. He had also visited New Orleans twice to do surveillance, the FBI further said.
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