There is a loss of E-cadherin that can lead to sex hormone dependent cancer
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A team of scientists, led by researchers from the Johns Hopkins University, have reported that a new class of drugs, GRPR, is being investigated for treatment of sex hormone-dependent cancer. The new drug works by blocking the action of Gastrin-Releasing Compound (GRC) on the S-cadherin peptide receptor. It has the ability to bind to both the S-cadherin peptide receptor and GRPR.