DGC structure rationalizes muscular dystrophy-causing genes
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Source: Native DGC structure rationalizes muscular dystrophy-causing mutations
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Source: Native DGC structure rationalizes muscular dystrophy-causing mutations
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Scientists have developed an adaptive regularisation technique for single-Tesla cryo-electron microscopy that allows them to measure and validate resolution in the 3D structure determination using a single-particle electron microscope. They used the technique to demonstrate that it improves the resolution of 3D structure determination in cryo-EM reconstruction. The technique is used to measure dissociation of the complex of dystrophin and its associated proteins into several groups.