Month: March 2025
The Trump team withdrew millions of dollars for addiction and mental health care
US President Donald Trump’s administration has cut 20,000 jobs in the Health and Human Services (HHS) department, as it restructures the department. The department includes the Centers for Disease Control and Prevention, the Centers for Medicare and Medicaid Services, the Food and Drug Administration, the National Institutes of Health (NIH) and other smaller divisions.
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A coronaviruses assembly drug that targets the viral vesicles
The images show H&E-stained left lung lobes of Syrian golden hamsters infected with SARS-CoV-2 and vehicle or JNJ-9676 treated. Cells were washed twice with PBS, the first wash was followed by the compound containing medium and the second was used to further the cells to 37 C. JNJ-9676 or vehicle was prepared in MucilAIR medium (Epithelix) and added on day 1 to the basal compartment of 24-well MucilAIR plates.
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The first map of human brain mitochondria is a groundbreaking achievement
The brains of a 54-year-old donor and a slice of frozen human brain were split into 703 tiny cubes, thanks to a tool used for woodworking. The cube size was similar to the units that make up Standard 3D images of the brain. Martin Picard, a co-author of the study, said the biology of the brain is deeply intertwined with the energetics of the brain.
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Drug-resistantbacteria was discovered in the technician’s garden
Researchers have discovered a peptide-based antibiotic molecule that targets a broad range of disease-causing bacteria and is not toxic to human cells. The molecule, namedlariocidin, binds to the ribosome and also transfer RNA, supplies ribosome with aminoacid building blocks it needs to string together peptide chains. Ultimately, this means that ribosome produces incorrect peptides, some of probably end up being toxic to the bacterium.
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Transient deletion of hypermutation preserves B cell affinity
We showed that large clusters of MCherry-expressing Histone-2b (H2b-mCherry) cells are enriched in GC B cells carrying affinity-enhancing mutations. Here, we observed that DZ B cells remained above the CDK2Low G0 threshold at 36 h after anti-DEC-OVA treatment and C-N ratios in DZ B cells remained steadily above the CDK2low G0 threshold within 30 min of anaphase.
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There are convergent vocal representations in the human forebrain
A team of researchers, led by a professor at the Harvard University, has revealed a potential mechanism by which sleep replay in zebra finch’s brain reveals premotor circuit structure for a skilled behavior. They found an uncoordinated sleep replay across hemispheres in zebra finches. The researchers added that their findings could lead to an understanding of how zebra finches work together as a group.
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Immune cells bandage wounds
Neuophils aid in wound healing by releasing extracellular matrix and other toxins, as observed in mice skin, lungs and intestinal organs by atomic force microscopy. The neutrophils stained for Col3a1 in their skin in WT control, as well as images from 2 mice, and TgfbrN mice. Further, independent experiments showed that fibre size can be determined in the skin of TgfbrN mice.
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Brain scans show we aren’t remembering being babies
Yale University neuroscientist Nick TurkBrowne has said that what happens in baby’s brain in the first two years of life is’magnificent’. “What happens in baby’s brain in the first two years of life is magnificent…better understanding how your brain learns…in infancy lays the foundation for everything you know and do for the rest of your life,” he added.
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How bad could the measles get in the US?
The US has reported its first case of measles in over 10 years after a six-year-old girl died from the disease, which is known to spread through airborne droplets if a person is too sick to breathe. Measles can spread through air droplets if a person is too sick to breathe. “If sparks from this initial fire land in communities where vaccination rates are low, then we’re going to have multiple large outbreaks,” a researcher said.
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Stone Age Europeans sailed by sea to Africa
Researchers have said that eastern Maghreb carried local indigenous hunter-gatherer ancestry similar to that of ancient people from what’s now Morocco. But unlike those western Maghreb hunter-gatherers, whose ancestry was largely replaced by European farmers probably arriving through the Strait of Gibraltar, the local ancestry persisted in Tunisia and Algeria long after the arrival of farmers from Europe and the Middle East.
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