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One million years ago, bone tools were used by humans

Scientists have identified antimicrobial peptides which could one day help protect humans against infections, a study claimed. The peptides were found in the fossilised remains of Homo erectus, a small-brained hominins, that lived between 1.8 and 1.5 million years ago, it added. A team of scientists from the University of Wisconsin-Madison and the Harvard Medical School had tested the peptides on mice.

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Single cell histone modifications are used for embryo tracing

A new study has found that genome-coverage single-cell histone modifications could be used to tracing lineages in embryos. Researchers used fragment counts in 5kb genome windows to assess genome coverage for all three of the histone modifications. This was done using data from a CoTACIT database of embryo lineages from pregnant female mice.

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There is anxiety over the future of its grants

US President Donald Trump’s administration has barred federal agencies from awarding any federal funding for scientific research. This comes after the administration froze all federal grants and loans to align it with his Executive Orders. It also cancelled review panels for research-grant funding and halted communications.

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The first in-womb treatment for motor-neuron condition is a success

Researchers trained an artificial intelligence engine on one-second slices of gameplay from online multiplayer game ‘B Bleeding Edge’, taken from controllers’ inputs. The engine, World and Human Action Model (WHAM), can create a world that responds to player inputs. WHAM was trained on one-second slices of gameplay taken from 5,00,000 anonymized play sessions.

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Despite lawsuits challenging Trump’s order, the research grant from the NIH is still frozen

US President Donald Trump’s administration has ordered Federal employees to post notices at least 35 days in advance of grant-review meetings, the Department of Government Efficiency said. If federal employees don’t do so, they would face “adverse consequences”, the department added. The notice will have to be posted at least 15 days prior to the grant-review meetings.

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UM171 glues to the asymmetric assembly to degrade the CoREST corepressors

Lentiviral particles carrying overexpression constructs were produced and used totransduce K562 KBTBD4-null CoREST–GFP cells. The particles were added with a final concentration of 40–0.006 M, and then incubated with DMSO for 72 h. The cells were selected with 2 g ml1 puromycin for three days, then sorted for single-cell clones on the BD FACSAria Cell Sorter (BD Biosciences).

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RFK Jr. was confirmed to be Trump’s health secretary

The US Senate has voted to confirm Ted Kennedy as the secretary of the Department of Health and Human Services (HHS), which oversees the FDA, Centers for Disease Control and Prevention and National Institutes of Health. Kennedy told the Senate that he supported vaccines and believes that they have saved lives. Kennedy can do a lot on vaccines including appointing advisors.

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The Heritage Foundation has reported on how the DEI staff was attacked by the National Institute of Health

The US National Institute of Allergy and Infectious Diseases (NIH) said it would reduce its indirect cost rate from 15% to 15%. It added that a recent analysis showed that 67 out of 72 universities were willing to accept research grants with no indirect cost coverage. However, the NIH did not answer questions about whether it would give more money to researchers.

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U.S. cannabis shoppers are faced with a market flush with illegal weed

Justin Singer, who makes edible cannabis products in Colorado under the names Ripple and Ript, said that anything that isn’t in the regulated market in the state shouldn’t be sold and that products derived from the plant have little to no safety regulations. He added, “There’s going to be mould and these banned pesticide and herbicides that are getting into the illegal product.”

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Product safety isn’t guaranteed even where weed is legal

A US-based edible marijuana manufacturer, Justin Singer, has said that he became concerned about the state’s lack of enforcement of the industry after he released a much cheaper product to the market and increased sales by 500%. As the industry became well established, Colorado’s Marijuana Enforcement Division began to require testing of marijuana for things like heavy metals and yeasts and molds.

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